Acupuncture and pharmacopuncture are as effective as morphine or carprofen for postoperative analgesia in bitches undergoing ovariohysterectomy

摘要

PURPOSE: To investigate the analgesic effect of acupuncture (AP) or micro-dose\udpharmacopuncture (PA), using carprofen or morphine, in bitches undergoing\udovariohysterectomy (OHE).\udMETHODS: Thirty five dogs were randomly assigned to five groups after sedation\udwith acepromazine IM: AP, 0.5 mg.kg(-1) of morphine subcutaneously (SC), 4\udmg.kg(-1) of carprofen SC, and PA with 0.05 mg.kg(-1) of morphine or 0.4\udmg.kg(-1) of carprofen. Anaesthesia was induced with propofol and maintained with\udisoflurane. Pain was assessed after OHE by a blind observer for 24h, by dynamic\udvisual analogue scale (DIVAS), Glasgow (CMPS-SF), Melbourne (UMPS) and Colorado\udUniversity pain scale (CSU). Animals reaching 33% of the UMPS score received\udrescue analgesia with morphine IM. Non parametric data were analysed by\udKruskal-Wallis or Friedman tests where applicable, followed by Dunn's test.\udParametric data were analysed by two way ANOVA, followed by Tukey test.\udRESULTS: There were no differences among groups in number of rescue analgesia.\udExcept for the DIVAS score where animals treated with morphine had the lowest\udscore compared with AP and carprofen, at 1h after surgery, there were no other\uddifferences among groups.\udCONCLUSION: Acupuncture or pharmacopuncture were equally effective as morphine or\udcarprofen to control postoperative pain in bitches undergoing ovariohysterectomy.